Pharmaceutics ll Exam 2 Practice

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A 45-year-old mechanically ventilated patient receives propofol 200 mg/h in a 10 mg/mL formulation in a 10% lipid emulsion. How many calories per day does this provide?

100

144

264

528

Propofol is given in a lipid emulsion, so the calories come from the fat in that emulsion. Convert the dose to volume: 200 mg/h at 10 mg/mL equals 20 mL/h. A 10% lipid emulsion provides about 1.1 kcal per mL, so hourly calories are 20 mL/h × 1.1 kcal/mL = 22 kcal/h. Over 24 hours, 22 × 24 = 528 kcal/day.

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